DARWIN Digitale Dissertationen German Version Strich

FU Berlin
Digitale Dissertation

Petra Lemnitz, geb. Schulze :
Immunhistochemical detection of the VEGF-receptor KDR in histologic sections of monkey tissues
Immunhistochemische Darstellung des VEGF-Rezeptors KDR in Affengeweben

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|Abstract| |Table of Contents| |More Information|

Abstract

Vascular endothelial growth factor (VEGF) plays a pivotal role in the regulation of angiogenesis under physiological conditions and in various diseases (i.e. neoplasia).Its activity is mediated through specific receptors like KDR (kinase-insert-domain-receptor, VEGF-receptor-2). In this study, the KDR was localized immunhistochemically in several normal tissues of monkeys. Its presence was found on endothelial cells as well as in other non-endothelial tissues, i.e. epithelium of glands, lymphocytes and smooth muscle cells. In the study in hand, the chondrocytes, muscle cells of the heart and the fibrocytes were identified as KDR-expressing structures for the first time.

Table of Contents

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Titelblatt, Inhaltsverzeichnis, Lebenslauf
1. Einleitung
2. Literaturübersicht
3. Eigene Untersuchungen
4. Diskussion
5. Zusammenfassung
6. Summary
7. Anhang
Literaturverzeichnis

More Information:

Online available: http://www.diss.fu-berlin.de/2002/176/indexe.html
Language of PhDThesis: german
Keywords: Monkeys; Endothelium; Blood Vessels
DNB-Sachgruppe: 34 Veterinärmedizin
Date of disputation: 24-May-2002
PhDThesis from: Fachbereich Veterinärmedizin, Freie Universität Berlin
First Referee: Prof. Dr. Roland Rudolph
Second Referee: PD R. Michael Schirner
Third Referee: Prof. Dr. Norbert-Christian Juhr
Contact (Author): PetraLemnitz@aol.com
Date created:19-Sep-2002
Date available:18-Feb-2003

 


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