FU Berlin Digitale Dissertation
Andreas Michael Heinrich Foerster : Investigation of bipolar cell function with electrophysical methods in retinal dystrophies Untersuchung der Bipolarzellfunktion mittels elektrophysiologischer Verfahren bei retinalen Dystrophien
|Abstract| |Table of Contents| |More Information|

Abstract Hereditary retinal dystrophies manifest themselves mostly with disturbances of the photoreceptor or the retinal pigment epithelium. It can come to a primary or secondary disturbance of the internal retinal layers. The ON and OFF responses are able to give a predicate about the function of the retinal bipolar cells. This study on 273 patients demonstrates the ability of electrophysiological methods to detect the place of the damage, degeneration or dystrophy by measurements of ON and OFF responses. In approx. 20 % of the cases a disturbance on the bipolar cell level could be proven. Thus it could be shown here at a larger collective that the bipolar cells are applicable possibly also as primary or main damage place with retinal degenerations. The investigation of the ON and OFF responses is a simple, well reproducible method, in order to examine the retina function on the bipolar cell level.

Table of Contents Download the whole PhDthesis as a zip-tar file or as zip-File For download in PDF format click the chapter title 0. Titelblatt 1. Einleitung 2. Anatomie und Physiologie der Netzhaut 2.1. Aufbau der Netzhaut 2.2. Aufbau und Funktion der Bipolarzellen 2.3. Erregungsleitung 3. Retinale Degeneration 3.1. Erworbene Netzhautdegeneration 3.2. Hereditäre Netzhautdystrophien 3.3. Stationäre Netzhautfunktionsstörungen 4. Material und Methoden 4.1. Ableittechnik für Elektroretinographie (ERG) 4.2. ERG-Ableitung des Studienlabors 4.3. Ableitung der ON- und OFF-Antworten 4.4. Patienten 5. Ergebnisse 5.1. Normalprobanden 5.2. Patienten 6. Diskussion 7. Zusammenfassung 8. Literatur 9. Danksagung 10. Lebenslauf

More Information:
Online available:	http://www.diss.fu-berlin.de/2001/174/indexe.html
Language of PhDThesis:	german
Keywords:	electrophysiology, ON/OFF-response, bipolar cells, retina, degeneration
DNB-Sachgruppe:	33 Medizin
Date of disputation:	07-Sep-2001
PhDThesis from:	Fachbereich Humanmedizin, Freie Universität Berlin
First Referee:	Prof. Dr. med. Ulrich Kellner
Second Referee:	Prof. Dr. med. Heinrich Bleckmann
Contact (Author):	amh.foerster@web.de
Date created:	03-Sep-2001
Date available:	07-Sep-2001

 

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